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- Third-party lab tested, pure Chrysin
Chrysin is most commonly used in bodybuilding as a healthy alternative to other unnatural compounds. It also assists muscle growth, acts as an energy booster, and aids in increasing athletic endurance.
Keywords: Anti-inflammatory; Antioxidant; Chrysin; Cytotoxic; Flavonoids; Health claims.
Chrysin is an ingredient in dietary supplements. As of 2016, there was no clinical use of chrysin, and no evidence for its effect on testosterone levels. In 2016, the US Food and Drug Administration did not recommend chrysin be included on the list of bulk drug substances that can be used in compounding under section 503A of the Federal Food, Drug, and Cosmetic Act.
Chrysin is a flavone under the category of flavonoids. It is widely distributed in plants and has been studied for antioxidant, antispasmodic, anxiolytic, and antiinflammatory activities. The antiinflammatory effect of chrysin was found most likely by the inhibition of COX-2 expression and via IL-6 signaling.
* The statements in this section have not been evaluated by the FDA or EFSA.
References
1. Naz, Saima et al. "Chrysin: Pharmacological and therapeutic properties." Life sciences vol. 235 (2019): 116797. doi:10.1016/j.lfs.2019.116797
2. Alavi Dana, Seyyed Mohammad Matin et al. "Chrysin Effect Against Gastric Cancer: Focus on its Molecular Mechanisms." Current molecular pharmacology vol. 16,7 (2023): 707-711. doi:10.2174/1874467216666230103105725
3. Ganai, Shabir Ahmad et al. "Plant flavone Chrysin as an emerging histone deacetylase inhibitor for prosperous epigenetic-based anticancer therapy." Phytotherapy research : PTR vol. 35,2 (2021): 823-834. doi:10.1002/ptr.6869
4. Gao, Song et al. "Developing nutritional component chrysin as a therapeutic agent: Bioavailability and pharmacokinetics consideration, and ADME mechanisms." Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie vol. 142 (2021): 112080. doi:10.1016/j.biopha.2021.112080
5. Liu, Xiaoxiao et al. "Pyrotinib and chrysin synergistically potentiate autophagy in HER2-positive breast cancer." Signal transduction and targeted therapy vol. 8,1 463. 18 Dec. 2023, doi:10.1038/s41392-023-01689-w
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