- 100% NATURAL PRODUCT: No artificial colors or flavors
- Verified herb identity, confirmed highest quality of raw materials and the extract
- Best natural sources of herbs and raw materials: Every vendor is carefully picked to meet our high standards
- Third-party lab tested, All natural Milk Thistle Extract
- Liver Cleanse Detox
Milk thistle (Silybum marianum) is a medicinal plant from the Asteraceae family. Silymarin is the major constituent of milk thistle extract and is a mixture of some flavonolignans such as silybin, which is the most active component of silymarin. It is most commonly known for its hepatoprotective effect.
Keywords: Silybum marianum; Silymarin; GLP-1; Silibinin;
Contaminants |
Arsenic (As) |
≤ 0.5 mg/kg |
Conforms |
GB 5009.76 |
Lead (Pb) |
≤ 0.5 mg/kg |
Conforms |
GB 5009.75 |
Mercury (Hg) |
≤ 0.1 mg/kg |
Conforms |
GB 5009.17 |
Cadmium(Cd) |
≤ 0.5 mg/kg |
Conforms |
GB 5009.15 |
Residual Acetone |
≤ 5,000 μg/g |
3.4x10³μg/g |
USP42 |
Residual Hexane |
≤ 290 μg/g |
16 μg/g |
USP42 |
Pesticide Residues |
Meet Reg. (EC) No 396/2005 |
Conforms |
Reg. (EC) No 396/2005 |
Microbiological |
Total Plate Count |
≤ 1,000 cfu/g |
Conforms |
GB 4789.2 |
Mold&Yeast |
≤ 100 cfu/g |
Conforms |
GB 4789.15 |
E. Coli |
<10 cfu/g |
Conforms |
GB 4789.38 |
Salmonella |
Absent/25g |
Conforms |
GB 4789.4 |
Staphylococcus aureus |
<10 cfu/g |
Conforms |
GB4789.10 |
Irradiation status |
Non irradiated, No ETO treated, Negative by PSL screen test. |
GMO/BSE Status |
Non-GMO, Free of BSE. |
* The statements in this section have not been evaluated by the FDA or EFSA.
References
1. Fallah M, Davoodvandi A, Nikmanzar S, et al. Silymarin (milk thistle extract) as a therapeutic agent in gastrointestinal cancer.
Biomed Pharmacother. 2021;142:112024. doi:10.1016/j.biopha.2021.112024
2. Wang J, Zhang L, Cao H, et al. Silibinin improves L-cell mass and function through an estrogen receptor-mediated antioxidative mechanism. Phytomedicine. 2022;99:154022. doi:10.1016/j.phymed.2022.154022
3. Zheng N, Liu L, Liu WW, et al. Crosstalk of ROS/RNS and autophagy in silibinin-induced apoptosis of MCF-7 human breast cancer cells in vitro. Acta Pharmacol Sin. 2017;38(2):277-289. doi:10.1038/aps.2016.117
4. Wang J, Zhang X, Zhang L, et al. Silychristin A activates Nrf2-HO-1/SOD2 pathway to reduce apoptosis and improve GLP-1 production through upregulation of estrogen receptor α in GLUTag cells. Eur J Pharmacol. 2020;881:173236. doi:10.1016/j.ejphar.2020.173236