Erythromycin thiocyanate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin thiocyanate binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid. Erythromycin thiocyanate also exhibits antitumor and neuroprotective effect in different fields of research.
The antimicrobial spectrum is similar to benzicillin, and it has a strong effect on Staphylococcus aureus, Streptococcus and Pneumococcus in Gram-positive bacteria, and also has a certain effect on Pasteurella and Brucella in Gram-negative bacteria.In addition, this product still is right mildewy body, rickettsia, leptospirosis, actinomycetes, noka fungus is effective, but to coliformis, salmona han belong to wait for intestinal negative bacilli to have no effect.
Erythromycin thiocyanate is mainly used for serious infections caused by drug-resistant Staphylococcus aureus and Streptococcus hemolyticus, such as pneumonia, septicemia, endometritis, mastitis, etc. It is also effective in the treatment of chronic respiratory disease in poultry and mycoplasma pneumonia in pigs caused by mycoplasma, and in the treatment of nocardia in dogs and cats; Erythromycin thiocyanate can also be used to prevent and control white head and white mouth disease in fry and fish species of green, grass, silver and bighead carp, grass carp and green carp. Erythromycin thiocyanate can also be used for the prevention and treatment of white head and white mouth disease in fry and fish species of green, grass, bighead and silver carp, grass carp, bacterial gill rot in green carp, white skin disease in bighead and silver carp and streptococcal disease in tilapia.
Erythromycin thiocyanate is a macrolide antibiotic that has a variety of effects, including:
-
Antimicrobial
Erythromycin thiocyanate has a broad spectrum of antimicrobial activity, binding to bacterial 50S ribosomal subunits to inhibit protein synthesis.
-
Antitumor and neuroprotective
Research has shown that erythromycin thiocyanate has antitumor and neuroprotective effects.
-
Antioxidant and anti-inflammatory
Erythromycin thiocyanate has antioxidant and anti-inflammatory effects, and can suppress the accumulation of 4-HNE and 8-OHdG.
-
Surface-binding properties
Erythromycin thiocyanate has strong surface-binding properties that are not affected by pH or salt concentration. This makes it a potential candidate for environmental applications like wastewater treatment.
-
Eye irritation
Erythromycin thiocyanate can cause serious eye irritation.
Erythromycin thiocyanate is an experimental drug that is used to treat infectious diseases. It has low solubility in water, which may limit its use as an oral drug.
Erythromycin thiocyanate is mainly used in the treatment of resistance to penicillin staphylococcus aureus, Infections caused by streptococcus, etc. Antibiotic medicine. Mainly used for gram-positie organisms and of the original body infection, is the domestic production for processing roxithromycin, Hu b erythromycin, Taspharmaceutical erythromycin thiocyanate priceess erythromycin, Carat erythromycin, Archie erythromycin series derivatives of an ideal material.
Erythromycin thiocyanate is mainly used in the treatment of resistance to penicillin staphylococcus aureus, Infections caused by streptococcus, etc. Antibiotic medicine. Mainly used for gram-positie organisms and of the original body infection, is the domestic production for processing roxithromycin, Hu b erythromycin, Taspharmaceutical erythromycin thiocyanate priceess erythromycin, Carat erythromycin, Archie erythromycin series derivatives of an ideal material.
|
* The statements in this section have not been evaluated by the FDA or EFSA.
References
1.Bernabéu JA, Camacho MA, Gil-Alegre ME, Torres-Suárez AI.J Agric Food Chem. 2001 Aug;49(8):3709-12. doi: 10.1021/jf010169b.PMID: 11513652
2.De Alwis HG, Girard L, Kijak PJ, Rummel N.J AOAC Int. 2013 Nov-Dec;96(6):1233-8. doi: 10.5740/jaoacint.12-368.PMID: 24645499
3.Bernabéu JA, Torres-Suárez AI, Gil-Alegre ME, Camacho MA.J Agric Food Chem. 2000 Dec;48(12):5969-74. doi: 10.1021/jf991212m.PMID: 11312770
4.Griessmann K, Kaunzinger A, Schubert-Zsilavecz M, Abdel-Tawab M.Pharmazie. 2007 Sep;62(9):668-71.PMID: 17944319