Premium Gastrodia Elata Extract with 20% Gastrodin for Nerve Health

• Customization: Available
• Certification: ISO, Halal
• Assay Method: HPLC-MS, HPLC
• Model NO.: NY012
• Application Form: Tablet, Capsule, Softgels
• Application: Food, Health Care Products, Medicine
• State: Powder
• Extract Source: Gastrodiae Elata BLUME
• Lead Time: 5 Days
• Transport Package: 1kg/Bag; 25kg/Drum
• Specification: Gastrodiae elata Blume
• Trademark: Nutrayours/ OEM
• Origin: China
• HS Code: 2938909090
• Production Capacity: 800kg/Year

Product Description

 

About this item

• 100% NATURAL PRODUCT: No artificial colors or flavors
• Verified herb identity, confirmed highest quality of raw herb and the extract
• Best natural sources of herbs and raw materials: Every vendor is carefully picked to meet our high standards
• Third-party lab tested, Natural Rhizoma Gastrodiae

 
  Gastrodiae Rhizoma is a highly valuable traditional herbal medicine commonly used to treat neurological disorders.

Rhizoma Gastrodiae, commonly known as Tianma, is a traditional Chinese medicine with a range of potential effects, particularly in the realm of neurological and cognitive health. It has been traditionally used to treat headaches, dizziness, vertigo, and convulsions. Modern research suggests it may have neuroprotective, anti-inflammatory, antioxidant, and even antidepressant properties. 

 

Keywords: Chronic unpredictable mild stress; Depression; Diabetes; Gastrodin; Glucolipid metabolism; Gastrodiae Rhizoma ethanol extract; apoptosis; cerebral ischemia-reperfusion injury; mitochondrial dysfunction; oxidative stress.

 

Function and efficacy

1. Neuroprotective Effects:

• Brain Aging:

  .Opens in new tab

  Studies suggest Rhizoma Gastrodiae can help attenuate brain aging by promoting antioxidant activity and neuroprotection. 

   
• Cognitive Impairment:

  .Opens in new tab

  It may protect against cognitive impairment, potentially by modulating the gut microbiota and influencing the expression of proteins like p-TauThr231. 

   
• Neurodegenerative Diseases:

  .Opens in new tab

  Research indicates it can be neuroprotective in models of Huntington's disease and Niemann-Pick type C disease. 

   
• Alzheimer's Disease:

  .Opens in new tab

  It has shown promise in protecting against beta-amyloid-induced neurodegeneration, a key factor in Alzheimer's disease. 

   
• Ischemia/Reperfusion Injury:

  .Opens in new tab

  Extracts like GEPS can reduce brain damage caused by ischemia/reperfusion and promote the expression of neurotrophic factors like BDNF. 

   
• Epilepsy:

  .Opens in new tab

  It may help delay the onset of status epilepticus and suppress acute seizures in temporal lobe epilepsy. 

   

2. Anti-inflammatory Effects:

• General Anti-inflammatory:

  Rhizoma Gastrodiae has been shown to have anti-inflammatory properties, potentially through the inhibition of pathways like NF-κB.
• Neuroinflammation:

  It can help reduce neuroinflammation, which is a key factor in various neurological conditions. 

   

3. Antioxidant Effects:

• Free Radical Scavenging:

  .Opens in new tab

  Active compounds in Rhizoma Gastrodiae, like vanillyl alcohol, vanillin, and p-hydroxybenzyl alcohol, can scavenge free radicals.
• Inhibition of Lipid Peroxidation:

  .Opens in new tab

  It can inhibit lipid peroxidation, a process that can damage cells and tissues. 

   

4. Other Potential Effects:

• Antidepressant Effects: Research in animal models suggests it may have antidepressant effects, potentially through modulation of monoamine oxidase activity, monoamine concentration, and the GABAergic system. 
   
• Analgesic Effects: It may have analgesic effects and help with neuropathic pain. 
   
• Sedative and Hypnotic Effects: It may have sedative and hypnotic effects. 
   
• Cardiovascular Benefits: It may have effects that are beneficial for cardiovascular health. 

 

About us

* The statements in this section have not been evaluated by the FDA or EFSA.


References

1. Zhao W, Wang J, Latta M, et al. Rhizoma Gastrodiae Water Extract Modulates the Gut Microbiota and Pathological Changes of P-Tau^Thr231 to Protect Against Cognitive Impairment in Mice. Front Pharmacol. 2022;13:903659. Published 2022 Jul 15. doi:10.3389/fphar.2022.903659

2. Duan X, Song N, Ma K, Tong Y, Yang L. The effects of protein-rich extract from Rhizoma Gastrodiae against cerebral ischemia/reperfusion injury via regulating MAPK and PI3K/AKT signaling pathway. Brain Res Bull. 2023;203:110772. doi:10.1016/j.brainresbull.2023.110772

3. Li C, Cao J, Chen Z, et al. Gastrodin alleviates the deterioration of depressive-like behavior and glucolipid metabolism promoted by chronic stress in type 2 diabetic mice. Eur J Pharmacol. 2024;973:176582. doi:10.1016/j.ejphar.2024.176582

4. Luo Y, Chen P, Yang LP, Duan XH. Zhongguo Zhong Yao Za Zhi. 2022;47(20):5564-5573. doi:10.19540/j.cnki.cjcmm.20220613.708

5.  Wang M, Dong W, Wang R, et al. Gastrodiae Rhizoma Water Extract Ameliorates Hypothalamic-Pituitary-Adrenal Axis Hyperactivity and Inflammation Induced by Chronic Unpredictable Mild Stress in Rats. Biomed Res Int. 2020;2020:8374614. Published 2020 Jun 10. doi:10.1155/2020/8374614