Traditional Chinese Medicine Natural Rhizoma Gastrodiae Cites Ok

• Customization: Available
• Certification: ISO, Halal
• Assay Method: HPLC-MS, HPLC
• Model NO.: NY012
• Application Form: Tablet, Capsule, Softgels
• Application: Food, Health Care Products, Medicine
• State: Powder
• Extract Source: Gastrodiae Elata BLUME
• Lead Time: 5 Days
• Transport Package: 1kg/Bag; 25kg/Drum
• Specification: Gastrodiae elata Blume
• Trademark: Nutrayours/ OEM
• Origin: China
• HS Code: 2938909090
• Production Capacity: 800kg/Year

Product Description

 

About this item

• 100% NATURAL PRODUCT: No artificial colors or flavors
• Verified herb identity, confirmed highest quality of raw herb and the extract
• Best natural sources of herbs and raw materials: Every vendor is carefully picked to meet our high standards
• Third-party lab tested, Natural Rhizoma Gastrodiae

 

Gastrodiae Rhizoma is the dried tuber of Gastrodia elata Bl. (Orchidaceae), 95% ethanol extract of which has protective effects on on MPP⁺-induced cytotoxicity in human dopaminergic SH-SY5Y cells 

Function and efficacy

 

We reviewed the central nervous system (CNS) effects of gastrodin in preclinical models of CNS disorders including epilepsy, Alzheimer's disease, Parkinson's disease, affective disorders, cerebral ischemia/reperfusion, cognitive impairment as well as the underlying mechanisms involved and, where possible, clinical data that support the pharmacological activities.  As a result, gastrodin possesses a broad range of beneficial effects on the above-mentioned CNS diseases, and the mechanisms of actions include modulating neurotransmitters, antioxidative, anti-inflammatory, suppressing microglial activation, regulating mitochondrial cascades, up-regulating neurotrophins, etc.  

  Gastrodiae Rhizoma is a highly valuable traditional herbal medicine commonly used to treat neurological disorders.

Keywords: Chronic unpredictable mild stress; Depression; Diabetes; Gastrodin; Glucolipid metabolism; Gastrodiae Rhizoma ethanol extract; apoptosis; cerebral ischemia-reperfusion injury; mitochondrial dysfunction; oxidative stress.

About us

* The statements in this section have not been evaluated by the FDA or EFSA.


References

1. Zhao W, Wang J, Latta M, et al. Rhizoma Gastrodiae Water Extract Modulates the Gut Microbiota and Pathological Changes of P-Tau^Thr231 to Protect Against Cognitive Impairment in Mice. Front Pharmacol. 2022;13:903659. Published 2022 Jul 15. doi:10.3389/fphar.2022.903659

2. Duan X, Song N, Ma K, Tong Y, Yang L. The effects of protein-rich extract from Rhizoma Gastrodiae against cerebral ischemia/reperfusion injury via regulating MAPK and PI3K/AKT signaling pathway. Brain Res Bull. 2023;203:110772. doi:10.1016/j.brainresbull.2023.110772

3. Li C, Cao J, Chen Z, et al. Gastrodin alleviates the deterioration of depressive-like behavior and glucolipid metabolism promoted by chronic stress in type 2 diabetic mice. Eur J Pharmacol. 2024;973:176582. doi:10.1016/j.ejphar.2024.176582

4. Luo Y, Chen P, Yang LP, Duan XH. Zhongguo Zhong Yao Za Zhi. 2022;47(20):5564-5573. doi:10.19540/j.cnki.cjcmm.20220613.708

5.  Wang M, Dong W, Wang R, et al. Gastrodiae Rhizoma Water Extract Ameliorates Hypothalamic-Pituitary-Adrenal Axis Hyperactivity and Inflammation Induced by Chronic Unpredictable Mild Stress in Rats. Biomed Res Int. 2020;2020:8374614. Published 2020 Jun 10. doi:10.1155/2020/8374614