| Customization: | Available |
|---|---|
| Certification: | ISO, Halal |
| Assay Method: | HPLC |
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Betulinic acid is a naturally occurring pentacyclic triterpenoid which has anti-retroviral, anti-malarial, and anti-inflammatory properties, as well as a more recently discovered potential as an anticancer agent, by inhibition of topoisomerase. It is found in the bark of several species of plants, principally the white birch (Betula pubescens) from which it gets its name
Betulinic acid, a natural pentacyclic triterpenoid compound, is an inhibitor of eukaryotic topoisomerase I (topoisomerase I) with IC50 value of 5 μM, and has anti-inflammatory, anti-malaria, anti-AIDS and anti-tumor activities.
| Analysis Items | Specifications | Results | Test Methods | ||||
| Identification | Positive | Conforms | HPLC | ||||
| Appearance | Fine brownish yellow powder | Conforms | Visual test | ||||
| Odor & Taste | Characteristic | Conforms | Organoleptic test | ||||
| Bulk Density | 45-55g/100ml | Conforms | ASTM D1895B | ||||
| Mesh Size | NLT 98% through 80 mesh | Conforms | AOAC 973.03 | ||||
| Solubility | Soluble in alcohol & water solution | Conforms | Visual | ||||
| Extract Ratio | 10:1 | 10:1 | / | ||||
| Loss on Drying | NMT 5% | 3.77% | 5g /105ºC /2hrs | ||||
| Ash Content | NMT 5% | 3.59% | 2g / 525C / 5hrs | ||||
| Extract Solvents | Ethanol & Water | Conforms | / | ||||
| Solvent Residues | NMT 0.05% | Conforms | GC | ||||
| Heavy Metals | NMT 10ppm | Conforms | Atomic Absorption | ||||
| Arsenic (As) | NMT 1ppm | Conforms | Atomic Absorption | ||||
| Lead (Pb) | NMT 2ppm | Conforms | Atomic Absorption | ||||
| Cadmium (Cd) | NMT 0.5ppm | Conforms | Atomic Absorption | ||||
| Mercury(Hg) | NMT 0.2ppm | Conforms | Atomic Absorption | ||||
| 666 | NMT 0.1ppm | Conforms | USP-GC | ||||
| DDT | NMT 0.5ppm | Conforms | USP-GC | ||||
| Acephate | NMT 0.2ppm | Conforms | USP-GC | ||||
| Parathion-ethyl | NMT 0.2ppm | Conforms | USP-GC | ||||
| PCNB | NMT 0.1ppm | Conforms | USP-GC | ||||
* The statements in this section have not been evaluated by the FDA or EFSA.
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